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2006-11-26 · Similarly, a mole of a molecular substance (6.022 × 1023 molecules) is the amount of the substance whose mass (in grams) is equal to its molecular weight. Molecular weight is derived by summing the atomic weights of the atoms composing a molecule. For example, 70.906 grams (2 × 35.453) of Cl2 contains 6.022 × 1023 molecules (one mole) of Cl2.